Thar Process is a sustainable global leader organization that deals in various CO2-based processes. Since 1990- Thar Process has been creating supercritical machines that have been helpful for CO2 extraction and purification of synthetic analogs for pharmaceuticals.
SCFE is most commonly used to extract supercritical carbon dioxide as a process fluid (sCO2). SCFE's capacity to extract the necessary chemicals in their purest form while simultaneously improving the process's efficiency, economy, and safety is the primary reason for its expanding popularity.
For thousands of years, traditional medicines, foods, and cosmetics have all been made with natural components. Plants are the most commonly used natural resource for medical purposes in folklore. Traditional folk medicines, such as ginseng roots, ginger rhizomes, and ginseng fruit, have all been widely used to relieve pain, reduce nausea, improve mood, and enhance cognitive function.
Using extraction techniques influenced by the idea that a natural product could be used as a weapon or a functional food to prevent or treat a variety of illnesses like cancer, neurological disorders, diabetes, bacterial infections, and cardiovascular diseases, modern drugs like penicillin and galantamine were discovered and produced today.
Numerous substances, such as carotenoids, -tocopherol, -humerene, -tocopheryl acetate and numerous oils, have been demonstrated to be beneficial to human health. There are numerous secondary metabolites found in plant-derived products, such as the terpenoids, alkaloids, and phenolic compounds mentioned above.
An SCFE Solvent that is Supercritical Fluid Extraction?
Carbon dioxide and water are the two most commonly used supercritical fluids. As a supercritical fluid, sCO2 has the following advantages:
At 31.10C, it has a low critical pressure of 73.9 bar, is non-flammable and non-toxic, and its density can be adjusted to increase its solvent power. It's also readily available in large quantities and pure form, all of which make it an attractive choice for use in a variety of compounds that are sensitive to temperature.
When CO2 is collected from the atmosphere and recycled, the SCFE process that employs CO2 becomes environmentally benign.
Solvent for SCFE in CO2: Carbon Dioxide (CO2) Extraction of Supercritical Fluids When extracting a component from a raw material, organic solvents are utilised to do it. Later, the organic solvent is separated from the dissolved component. This is a problem since organic solvents don't completely separate from the material, resulting in residues.
A variety of techniques are available for obtaining components of interest, which are commonly mixed with inactive components before further separation to disclose the molecules. In addition to simple methanol-based extraction methods, there are also Soxhlet and steam distillation methods that are considered traditional approaches.
However, these extraction methods have a number of drawbacks, such as the necessity for additional operations to remove toxic processing solvents and the destruction of heat-labile compounds in many circumstances. While some of the methods can provide a high yield of a certain spectrum of compounds depending on the solvent used, others of these methods are extremely selective for a small number of compound types.
When comparing the effectiveness of various processes, the Soxhlet method is the most used method of lipid extraction. As a result, these extraction technologies are not only notoriously unsuccessful since they yield so little bioactive extract in proportion to the large energy input, but they also pose a significant environmental concern because so much organic waste must be disposed of.